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Effects of nuruk extracts on cellular melanin content. Melanin contents were determined in B16F1 cells treated with 100 µg/mL of nuruk extracts and 100 µg/mL of arbutin for 72 hr. Arbutin was used as a positive control. Values represent mean ± SD (n = 3). Different letters indicate a significant difference (p < 0.01) based on one-way ANOVA and the Duncan's test. a-MSH, alpha-melanocyte stimulating hormone.
