Table 3.
First Author, Year, Study Place | Data Collection Period | Study Design | Sample Size | Nutritional Assessment | Quality of Life Assessment | Groups being compared | Key results | Conclusion |
---|---|---|---|---|---|---|---|---|
Scott HR, 2003, UK [28] | NA | Prospective | 106 inoperable NSCLC (stage III and IV) By stage – Stage III: n = 78 Stage IV: n = 28 |
Weight loss* * defined as loss of more than 5% pre-illness weight in the previous 6 months |
EORTC-QLQ-C30 | Weight-stable (< 5% weight loss) (n = 61) &Weight-losing (> 5% weight loss) (n = 45) |
(a) Global QoL: Median (range) = 50 (0–100) & 33.3 (0–66.7) respectively for weight-stable & weight-losing groups, p = 0.027. (b) Symptom scores: Fatigue (P < 0.05) and pain (P < 0.01) were significantly greater in the weight-losing group. i. Fatigue: – Median (range) = 55.6 (0–100) & 66.7 (0–100) respectively for weight-stable & weight-losing groups, p = 0.044. ii. Pain: – Median (range) = 16.7 (0–100) & 41.7 (0–100) respectively for weight-stable & weight-losing groups, p = 0.007. |
Weight loss has an impact on different aspects of quality of life. |