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. 2012 Apr 24;11:27. doi: 10.1186/1475-2891-11-27

Table 3.

Nutritional status and quality of life in lung cancer

First Author, Year, Study Place Data Collection Period Study Design Sample Size Nutritional Assessment Quality of Life Assessment Groups being compared Key results Conclusion
Scott HR, 2003, UK [28] NA Prospective 106 inoperable NSCLC (stage III and IV)
By stage –
Stage III: n = 78
Stage IV: n = 28
Weight loss*
* defined as loss of more than 5% pre-illness weight in the previous 6 months
EORTC-QLQ-C30 Weight-stable (< 5% weight loss) (n = 61) &Weight-losing (> 5% weight loss) (n = 45) (a) Global QoL:
Median (range) = 50 (0–100) & 33.3 (0–66.7) respectively for weight-stable & weight-losing groups, p = 0.027.
(b) Symptom scores: Fatigue (P < 0.05) and pain (P < 0.01) were significantly greater in the weight-losing group.
i. Fatigue: –
Median (range) = 55.6 (0–100) & 66.7 (0–100) respectively for weight-stable & weight-losing groups, p = 0.044.
ii. Pain: –
Median (range) = 16.7 (0–100) & 41.7 (0–100) respectively for weight-stable & weight-losing groups, p = 0.007.
Weight loss has an impact on different aspects of quality of life.