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. 2012 May 7;11:13. doi: 10.1186/1476-0711-11-13

Table 1.

Minimum inhibitory concentrations (MIC; μg/mL) of different statins against standard bacteria

Statins
Rosuvastatin
Atorvastatin
Simvastatin
  MIC; μg/mL MIC; μg/mL MIC; μg/mL
E. coli ATTC 35218
104.17 ± 36.08
26.04 ± 9.02*
52.08 ± 18.04
P. aeruginosa ATTC 9027
166.67 ± 72.16
83.33 ± 36.08
166.67 ± 72.16
MSSA ATTC 25213
208.33 ± 72.16
41.67 ± 18.04*
26.04 ± 9.02*
MRSA ATTC 43300
500 ± 0.00
83.33 ± 36.08*
166.67 ± 72.16*
S. pneumoniae ATTC 25923
333.33 ± 144.33
104.17 ± 36.08
166.67 ± 72.16
VSE ATTC 19433
333.33 ± 144.33
83.33 ± 36.08*
52.08 ± 18.04*
VRE ATTC 51299
500 ± 0.00
166.67 ± 72.16*
104.17 ± 36.08*
A. baumannii ATTC 17978
333.33 ± 144.33
15.62 ± 0.00*
104.17 ± 36.08*
P. mirabilis ATTC 12459
250 ± 0.00
62.5 ± 0.00*
166.67 ± 72.16
K. pneumoniae ATTC 13883
333.33 ± 144.33
166.67 ± 72.16
166.67 ± 72.16
S. pyogenes ATTC 19615
166.67 ± 72.16
83.33 ± 36.08
62.5 ± 0.00
H. influenzae ATTC 29247
166.67 ± 72.16
83.33 ± 36.084
52.08 ± 18.04
S. epidermidis ATTC 12228
166.67 ± 72.16
20.83 ± 9.02*
26.04 ± 9.02*
E. aerogenes ATTC 29751
104.17 ± 36.08
15.62 ± 0.00*
26.04 ± 9.02*
C. freundii ATTC 8090
166.67 ± 72.16
83.33 ± 36.08
52.08 ± 18.04
E. cloacae ATTC 13047 166.67 ± 72.16 41.67 ± 18.04* 62.5 ± 0.00

MICs were determined using serial dilution method according to the procedures National Committee for Clinical Laboratory Standards.

* indicates significant difference from rosuvastatin group.