. Author manuscript; available in PMC: 2013 Mar 1.

Published in final edited form as: Exp Hematol. 2011 Dec 8;40(3):187–196. doi: 10.1016/j.exphem.2011.11.009

Table 1.

Pre-transplant and post-transplant data from L09025, K09175, and T09214.^*

	L09025	K09175	T09214
Age	6 mo.	7 mo.	8 mo.
Weight	1.2 kg	1.0 kg	1.3 kg
Sex	Male	Female	Female
Transduction efficiency	46% (YFP)	35% (YFP)	41% (YFP)
	46% (GFP)	45% (GFP)	42% (GFP)
Fold expansion YFP arm (over 3 days)	3	13	19
Fold expansion GFP arm (over 9 days)	78	155	204
Transplant Dose	1.0⁵YFP+CD34+/kg	1.8⁵YFP+CD34+/kg	7.8⁵YFP+CD34+/kg
	2.6⁶GFP+CD34+/kg	3.3⁶GFP+CD34+/kg	3.4⁶GFP+CD34+/kg
Time to ANC > 500/μl (days)	19	7	10
Survival post-transplant (days)	82	45	270+
Outcome	TTP-like syndrome	Viral pneumonia	Alive

This table provides a summary of relevant information, including age and weight at time of transplant, transduction efficiencies, fold expansion of YFP and GFP experimental arms, transplant dose, time to neutrophil recovery, and post-transplant survival.