Table 2. Effect of trophoblastic-restricted ShRNA- mediated Sprn knockdown on embryo resorption at E13.5.
| Lentivirus | FoxL2 | FoxL2 | Shadoo (LS2) | Shadoo (LS2) | Shadoo (LS1) |
| Genetic Background | FVB/N | FVB/N Prnp 0/0 | FVB/N | FVB/N Prnp 0/0 | FVB/N Prnp 0/0 |
| Implanted | 37 | 24 | 44 | 40 | 66 |
| Resorbed | 19 | 9 | 17 | 40 | 40 |
| % Resorbed | 51.3 | 37.5 | 38.6 | 100* | 60.6 |
*
p<0.05 (x2 test) when compared to any of the other results.
These data are a compilation of at least 2 independent experiments. No statistically significant variability was observed between the analyzed litters (more than 4 for each lentiviral infections).