Table 3. Summary of results from different comparative genetic models.
-2518A/G | Na | Cases/Controls | GG vs. GA+AA | GG+GA vs. AA | G vs. A | |||
OR(95%CI) | Pb | OR(95%CI) | Pb | OR(95%CI) | Pb | |||
Total | 13 | 5341/6075 | 1.67(1.25, 2.23) | 0.0006 | 1.60(1.17, 2.18) | 0.003 | 1.46(1.15, 1.86) | 0.002 |
Asian | 7 | 1394/1583 | 1.79(1.19, 2.70) | 0.005 | 1.87(1.18, 2.95) | 0.007 | 1.58(1.14, 2.18) | 0.005 |
Afrian | 2 | 2187/2462 | 1.28(0.45, 3.64) | 0.65 | 1.12(0.53, 2.34) | 0.77 | 1.13(0.58, 2.24) | 0.72 |
Latino | 3 | 1329/1549 | 2.15(1.32, 3.51) | 0.002 | 1.90(0.97, 3.72) | 0.06 | 1.76(1.16, 2.68) | 0.008 |
South African Colored | 1 | 431/481 | 0.75(0.45, 1.25) | 0.27 | 0.82(0.63, 1.06) | 0.14 | 0.83(0.67, 1.03) | 0.09 |
SAC: South African Coloureds. a, number of case-control studies; b, p value for z-test.