Table 2. Regression analysis of ephrinA5 small isoform (ephrinA5S) in relation to clinical parameters.
Parameters | Category | No. of patient | EphrinA5S | ||
β | 95% CI | P | |||
Sex | Female | 23 | |||
Male | 119 | −0.96 | −0.281, 0.088 | 0.303 | |
Age (years) |
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58 | |||
>55 | 84 | 0.069 | 0.001, 0.138 | 0.048* | |
HBsAg | Negative | 34 | |||
Positive | 108 | −0.007 | −0.167, 0.153 | 0.930 | |
Anti-HCV | Negative | 94 | |||
Positive | 48 | 0.099 | −0.044, 0.242 | 0.175 | |
Alcoholism | Negative | 97 | |||
Positive | 45 | −0.081 | −0.227, 0.065 | 0.274 | |
Cirrhosis | Absence | 44 | |||
Presence | 98 | −0.109 | −0.255, 0.038 | 0.145 | |
Microvascular invasion | Absence | 88 | |||
Presence | 54 | −0.048 | −0.188, 0.093 | 0.504 | |
Macrovascular invasion | Absence | 105 | |||
Presence | 37 | 0.030 | −0.125, 0.185 | 0.704 | |
Histology grading |
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35 | |||
> II | 107 | 0.087 | 0.010, 0.165 | 0.028* | |
Capsule | Absence | 45 | |||
Presence | 97 | 0.049 | −0.098, 0.195 | 0.513 | |
Largest tumor size (diameter, cm) | □ 3 | 51 | |||
>3 | 91 | 0.037 | −0.105, 0.180 | 0.603 | |
Ascites | Absence | 126 | |||
Presence | 16 | −0.114 | −0.329, 0.101 | 0.296 | |
Alpha-fetoprotein (ng/mL) | □ 10.0 | 41 | |||
>10.0 | 101 | 0.012 | −0.139, 0.162 | 0.879 | |
Albumin (g/L) | <4.0 | 56 | |||
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86 | 0.064 | −0.075, 0.203 | 0.365 | |
Bilirubin (mg/dL) | <0.9 | 44 | |||
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98 | −0.076 | −0.223, 0.071 | 0.311 | |
Prothrombin time (sec) | □ 12.0 | 79 | |||
>12.0 | 63 | 0.037 | −0.100, 0.175 | 0.591 | |
Creatinine (mg/dL) | □ 1.0 | 75 | |||
>1.0 | 67 | −0.080 | −0.216, 0.056 | 0.244 | |
AST (U/L) | □ 52 | 88 | |||
>52 | 54 | 0.072 | −0.068, 0.212 | 0.311 | |
ALT (U/L) | □ 111 | 114 | |||
>111 | 28 | −0.048 | −0.219, 0.123 | 0.578 |
P<0.05.