Table 1. Summary Data from Depression Treatment Trials Based on Type of Treatment and Source of Data.

Treatment Type and Source	Number of Treatment Arms	Number of Patients
FDA Summary Basis of Approval Reports
Investigative Agents	80	7,014
Active Comparators	31	2,220
Placebo Controls	57	4,568
Column Totals	168	13,802
Published Depression Treatment Trials
Active Treatments
Combination Therapy + Antidepressants	32	1,249
Antidepressants + Clinical Management	40	1,958
Accepted Psychotherapies for Depression	128	4,034
Alternative Therapies for Depression	18	442
Column Totals	218	7,683
Treatment Controls
Pill Placebo Controls	16	412
Intervention Controls	48	1,095
Treatment as Usual Controls	12	530
Waiting-list Controls	34	590
Column Totals	110	2,627

Specific names of treatment arms for accepted depression treatments and treatment controls are shown as Appendix B.