Table 2.
Anal Cytology and HPV Results for Subjects Diagnosed with Anal Intraepithelial Neoplasia (AIN) 2–3
| VISIT 1 | VISIT 2 | VISIT 3 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| # | Anal Cytology Result | Anal HPV | HRA Result | Days to HRA Result† | Anal Cytology Result | Anal HPV | HRA Result | Days to HRA Result† | Anal Cytology Result | Anal HPV | HRA Result | Days to HRA Result† |
| 1 | LSIL | − | AIN2 | 90 | ||||||||
| 2 | LSIL | + | AIN3 | 41 | ||||||||
| 3 | LSIL | + | AIN3 | 125 | ||||||||
| 4 | NILM | − | N/A | N/A | NILM | + | AIN2 | 363 | ||||
| 5 | ASCUS | + | AIN1 | 52 | ASCUS | + | AIN2 | 283 | ||||
| 6 | ASCUS | + | Refused | N/A | LSIL | + | AIN2 | 615 | ||||
| 7 | LSIL | − | AIN1 | 30 | LSIL | − | AIN2 | 219 | ||||
| 8 | LSIL | − | AIN1 | 30 | ASCUS | + | AIN2 | 240 | ||||
| 9 | ASCUS | + | Refused | N/A | ASCUS | + | AIN3 | 346 | ||||
| 10 | NILM | − | N/A | N/A | LSIL | − | AIN3 | 265 | ||||
| 11 | ASCUS | − | AIN1 | 125 | NILM | − | N/A | N/A | ASCUS | − | AIN3 | 895 |
| 12 | NILM | + | Not Referred* | N/A | ASCUS | + | NILM | 419 | LSIL | + | AIN3 | 1154 |
Note: HPV, human papillomavirus; HRA, high resolution anoscopy; NILM, no intraepithelial lesion or malignancy; ASCUS, atypical squamous cells of undetermined significance; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; AIN, anal intraepithelial neoplasia; N/A, not applicable.
†
Days from baseline cytology result to HRA.
*
Visit 1 occurred prior to decision to refer subjects with isolated HPV+ for HRA.