Table 2.
Hub nodes of the brain morphological networks for high-risk schizophrenia neonates and control neonates. Both groups of neonates have hub nodes (denoted in bold) in frontal, temporal, insula, and limbic lobes. High-risk neonates have less hub nodes in parietal and subcortical lobes than control neonates, but have additional hub nodes in occipital lobe. Anatomical regions are classified as Primary, Associations, Paralimibic, and Subcortical as described by Achard et al. (2006).
| Anatomical Regions | Betweenness (×102) | ||||
|---|---|---|---|---|---|
|
| |||||
| Lobe | Abbreviation | Region | Class | High-risk Neonates | Control Neonates |
| Frontal | IFGoperc-L | Inferior frontal gyrus (opercular) left | Association | 0.0 | 3.7 |
| MFG-L | Middle frontal gyrus left | Association | 3.1 | 0.3 | |
| ORBinf-R | Orbitofrontal cortex (inferior) right | Association | 5.0 | 0.3 | |
| ORBmed-R | Orbitofrontal cortex (medial) right | Association | 6.1 | 0.7 | |
| REC-R | Rectus gyrus right | Paralimbic | 5.2 | 0.5 | |
| ROL-L | Rolandic operculum left | Association | 1.2 | 4.4 | |
| ROL-R | Rolandic operculum right | Association | 3.0 | 3.8 | |
| SFGdor-L | Superior frontal gyrus (dorsal) left | Association | 1.9 | 4.7 | |
| SMA-R | Supplementary motor area right | Association | 0.1 | 4.5 | |
|
| |||||
| Parietal | ANG-L | Angular gyrus left | Association | 1.9 | 3.1 |
| IPL-L | Inferior parietal lobule left | Association | 1.6 | 3.0 | |
| SMG-L | Supramarginal gyrus left | Association | 0.0 | 3.0 | |
| SMG-R | Supramarginal gyrus right | Association | 3.2 | 3.1 | |
|
| |||||
| Occipital | CUN-R | Cuneus right | Association | 3.2 | 0.5 |
| MOG-L | Middle occipital gyrus left | Association | 3.2 | 0.9 | |
| IOG-R | Inferior occipital gyrus right | Association | 5.0 | 1.0 | |
|
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| Temporal | HES-L | Heschl gyrus left | Primary | 2.1 | 4.2 |
| ITG-L | Inferior temporal gyrus left | Association | 4.4 | 0.4 | |
| MTG-R | Middle temporal gyrus right | Association | 7.5 | 2.1 | |
| STG-L | Superior temporal gyrus left | Association | 0.0 | 2.7 | |
| TPOmid-R | Temporal pole (middle) right | Paralimbic | 1.1 | 4.0 | |
| TPOsup-L | Temporal pole (superior) left | Paralimbic | 0.3 | 3.2 | |
| TPOsup-R | Temporal pole (superior) right | Paralimbic | 1.6 | 2.8 | |
|
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| Insula | INS-L | Insula left | Paralimbic | 3.7 | 0.7 |
| INS-R | Insula right | Paralimbic | 0.6 | 3.3 | |
|
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| Limbic | ANG-L | Anterior cingulate gyrus left | Association | 0.0 | 3.5 |
| PHG-R | ParaHippocampal gyrus right | Paralimbic | 3.2 | 0.5 | |
|
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| Subcortical | PAL-L | Pallidum left | Subcortical | 0.8 | 2.7 |
| THA-R | Thalamus right | Subcortical | 1.1 | 3.1 | |