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. Author manuscript; available in PMC: 2013 Jul 26.
Published in final edited form as: Neuron. 2012 Jul 26;75(2):306–319. doi: 10.1016/j.neuron.2012.05.018

Figure 3. Shh expression confers a survival advantage to dopaminergic neurons.

Figure 3

(A) Shh expressing DA neurons in Shh-nLZC/C; Dat-Cre mice at 12 months of age.

(B) Incidence of Shh expression in the SNpc in Shh-nLZC/C; Dat-Cre mice at 1 and 12 months of age (*p < 0.05, unpaired t-test, n=12/group, 100 cells/subject).

(C) Somatic area of Th+, Shh− - and Th+, Shh+ cells in the SNpc of Shh-nLZC/C; Dat-Cre mice (*p < 0.05, single comparison by Mann-Whitney U test; box-whisker plots for median ± 95% CI bar, 25-75 percentiles box, n=4, 20 cells/subject).