. Author manuscript; available in PMC: 2012 Jul 31.

Published in final edited form as: J Comp Neurol. 2001 May 7;433(3):415–425. doi: 10.1002/cne.1149

TABLE 2.

Cholinergic Cell Characteristics in the NPC Mouse¹

	NPC^+/+		NPC^−/−
Brain region	Cell no.	Cell size	Cell no.	Cell size
Basal forebrain	70.7 ± 8.2	—	77.7 ± 2.2	—
Striatum	77.5 ± 9.2	15.11 ± 0.36	69.0 ± 13	16.51 ± 0.24^*

Numbers for basal forebrain and strinatal neurons represent the mean ± SEM number of ChAT-immunostained neurons/20-µm-thick section. In each brain region there were n = 4 mice/group. Cells were counted in sections that were closely matched across brains to represent the same neuroantomical portion of each nucleus. The basal forebrain cells were located within several nuclei including the nucleus accumbens, substantia innominata, and nucleus basalis magnocellularis. Cell size represents the long axis, in µm, of only ChAT-immunostained somata with an unstained nucleus (n = 3/group).

Welch’s t = 3.23 (P = 0.038), NPC^+/+ vs. NPC^−/− cell size.