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Shown are representative photomicrographs (4X) of mouse rectums after the treatment protocol. Mouse colons were fixed, sectioned, and stained with hematoxylin and eosin. Tumor morphology was assessed for degree of atypia by an experience pathologist (TSS). Tumors that developed after AOM and DSS treatment in the WT and KO groups were typical adenomas with no apparent morphologic differences between groups.
