Table 1. DPβ1 pocket 1–4 amino-acid signature of DP supertypes.
| Supertypea | DP 1 | DP 2 | DP 3 | DP 4 | DP 6 | DP 8 | DP 11 | DP 15 |
|---|---|---|---|---|---|---|---|---|
|
Pocket 1–4 signatureb |
Asp84-Lys69 |
Gly84-Glu69 |
Asp84-Lys69 |
Gly84-Lys69 |
Asp84- Glu69 |
Asp84-Glu69 |
Asp84-Arg69 |
Val84-Arg69 |
| 0101 | 0201 | 0301 | 0401 | 0601 | 0801 | 1101 | 1501 | |
| 0501 | 0202 | 1401 | 0402 | 0901 | 1601 | |||
| DPB1 | 5001 | 3301 | 2001 | 2301 | 1001 | 1901 | ||
| alleles | 4801 | 2501 | 2401 | 1301 | ||||
| 2601 | 4901 | 1701 | ||||||
| 3501 | 5101 | 2101 | ||||||
| 3001 |
Abbreviations: Asp, aspartic acid; Arg, arginine; Gly, glycine; Glu, glutamic acid, Leu, leucine; Lys, lysine; Val, valine.
a
DP supertypes (1–4, 6, 8, 11, 15) are assigned from amino-acid residues lining peptide pockets 1, 4 and 6 of the DPβ1 domain.
b
Pocket 1–4 amino-acid signature shows residues at positions 84 and 69 of the DPβ1 domain.