Table 2. Frequency of DPβ1 pocket 1-4 amino-acid signatures in ALL patients who relapse.
| DPβ1 |
Frequency (%) of patients with signature |
||||
|---|---|---|---|---|---|
| amino-acid signature | DP supertype | Total n=798 | Relapse n=294 | Non-relapse n=504 | P (relapse vs non-relapse) |
| Asp84-Lys69 | DP 1+DP 3 | 248 (31) | 102 (35) | 146 (29) | 0.09 |
| Gly84-Glu69 | DP 2 | 161 (20) | 56 (19) | 105 (21) | 0.5 |
| Gly84-Lys69 | DP 4 | 655 (83) | 242 (83) | 413 (83) | 0.9 |
| Asp84-Glu69 | DP 6+DP 8 | 117 (15) | 42 (14) | 75 (15) | 0.8 |
| Asp84-Arg69 | DP 11 | 12 (2) | 5 (2) | 7 (1) | 0.8 |
| Val84-Arg69 | DP 15 | 34 (4) | 10 (3) | 24 (5) | 0.4 |
Abbreviations: ALL, acute lymphoblastic leukemia; Asp, aspartic acid; Arg, arginine; Gly, glycine; Glu, glutamic acid, Leu, leucine; Lys, lysine; Val, valine.