Table 3. Variants and loci suggested to associate with WHR in GWAS.

Regional gene(s)	Chromosome	SNP ID	SNP type	RAFa	Effect size WHR	Discovery study
LYPLAL1	1q41	rs2605100b	Intergenic	0.69	0.040	28
		rs4846567		0.28	0.034	30
RSPO3	6q22	rs9491696c	Intronic	0.52	0.042	30
VEGFA	6p12	rs6905288c	Intergenic	0.56	0.036	30
TBX15, WARS2	1p11	rs984222c	Intronic	0.37	0.034	30
NFE2L3	7p15	rs1055144c	Intergenic	0.21	0.040	30
GRB14	2q24	rs10195252c	Intergenic	0.60	0.033	30
DNM3, PIGC	1q24	rs1011731c	Intronic	0.57	0.028	30
ITPR2, SSPN	12p11	rs718314c	Intergenic	0.74	0.030	30
LY86	6p25	rs1294421c	Intergenic	0.39	0.028	30
HOXC13	12q13	rs1443512c	Intergenic	0.24	0.031	30
ADAMTS9	3p14	rs6795735c	Intergenic	0.41	0.025	30
ZNRF3, KREMEN1	22q12	rs4823006c	Intergenic	0.57	0.023	30
NISCH, STAB1	3p21	rs6784615c	Intronic	0.94	0.043	30
CPEB4	5q21	rs6861681c	Intronic	0.34	0.022	30

Abbreviations: GWAS, genome-wide association studies; RAF, risk allele frequency; SNP, single-nucleotide polymorphism; WHR, waist-to-hip ratio.

^aRAF and effect size from first discovery study.

^bAssociation restricted to women.

^cIdentified through meta-analyses of GWAS.