Table 3.
Diagnostic performances of non invasive means for the prediction oesophageal varices and large oesophageal varices in the training sample.
| AUROC ±SE | Cut-off | TP (n) | TN (n) | SS (%) | SP (%) | PPV (%) | NVP (%) | DA (%) | LR+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| Oesophageal varices | ||||||||||
| Platelet count | 0.768 ± 0.06 | <110500 | 68 | 18 | 80 | 69 | 89.5 | 51 | 77.5 | 2.6 |
| Spleen diameter | 0.679 ± 0.06 | >140 | 44 | 18 | 51.8 | 72 | 86.3 | 30.5 | 55.9 | 1.9 |
| PC/SD ratio | 0.793 ± 0.06 | ≤868 | 70 | 20 | 82.4 | 76.9 | 92.1 | 57.1 | 81.1 | 3.6 |
| Regression function | 0.879 ± 0.04 | 0.3 | 82 | 7 | 96.5 | 28 | 82 | 70 | 80.9 | 1.3 |
| 0.4 | 81 | 7 | 95.3 | 28 | 81.8 | 63.6 | 80 | 1.3 | ||
| 0.5 | 80 | 10 | 94.1 | 40 | 84.2 | 66.7 | 81.8 | 1.6 | ||
| 0.6 | 79 | 17 | 92.9 | 68 | 90.8 | 73.9 | 87.3 | 2.9 | ||
| 0.7 | 69 | 18 | 81.2 | 72 | 90.8 | 52.9 | 79.1 | 2.9 | ||
| 0.8 | 62 | 18 | 72.9 | 72 | 89.9 | 43.9 | 72.7 | 2.6 | ||
| Large oesophageal varices | ||||||||||
| Platelet count | 0.688 ± 0.06 | <106500 | 61 | 20 | 78.2 | 60.6 | 82.4 | 54.1 | 73 | 2 |
| Spleen diameter | 0.732 ± 0.05 | >137 | 49 | 25 | 62.8 | 46.3 | 86 | 46 | 66.7 | 1.2 |
| PC/SD ratio | 0.752 ± 0.06 | ≤897 | 66 | 21 | 84.6 | 63.6 | 84.6 | 61.8 | 78.4 | 2.3 |
| 0.3 | 75 | 9 | 96.2 | 28.1 | 76.5 | 75 | 76.4 | 1.3 | ||
| Regression function | 0.850 ± 0.04 | 0.4 | 73 | 11 | 93.6 | 34.4 | 77.7 | 68.8 | 76.4 | 1.4 |
| 0.5 | 68 | 15 | 87.2 | 46.9 | 80 | 60 | 75.5 | 1.6 | ||
| 0.6 | 64 | 20 | 82.1 | 62.5 | 84.2 | 58.8 | 76.4 | 2.2 | ||
| 0.7 | 59 | 25 | 75.6 | 78.1 | 89.4 | 56.8 | 76.4 | 3.5 | ||
| 0.8 | 51 | 27 | 65.4 | 84.4 | 91.1 | 50 | 71 | 4.2 |
AUROC: area under receiver operating characteristic curve, SE: standard error, PC/SD ratio: platelet count-spleen diameter ratio, TP: true positive TN: true negative SS: sensitivity SP: specificity PPV: positive predictive value NVP: negative predictive value DA: diagnostic accuracy, LR+: positive likelihood ratio, Prevalence of OV: 76.6%, logistic regression analysis was computed on 110 patients due to one missing value in those with no OV.