Table 1.

Values of the organ damage index^∗ (ODI) calculated for the liver and kidney of zeabra-seabreams exposed to the different treatments. No lesions were observed in control fishes. MeHg: exposure to Methylmercury; HgII: exposure to Hg²⁺; MeHgSe: coexposure to MeHg and Se; HgSe: coexposure to Hg²⁺ and Se; MeHgRSe: exposure to MeHg followed by exposure to Se during depuration; HgRSe: exposure to Hg²⁺ followed by exposure to Se during depuration; Se: exposure to selenium.

	Organ lesion (OL)	Pi	MeHg		HgII		MeHgSe		HgSe		MeHgRSe	HgRSe	Se
			d28	d42	d28	d42	d28	d42	d28	d42	d42	d42	d28	d42
			N OL	N OL	N OL	N OL	N OL	N OL	N OL	N OL	N OL	N OL	N OL	N OL
Liver	Architectural pattern lost	1	4	3	4	4	3	2	4	0	3	3	2	0
	Vacuolar degeneration	1	3	1	4	1	2	0	1	2	3	3	2	0
	Hydropic degeneration	1	4	2	3	1	1	2	1	1	0	3	0	0
	Hypertrophy of hepatocytes	2	2	3	1	4	4	0	4	1	0	0	0	0
	Extensive focal necrosis	3	0	3	2	4	0	2	1	3	0	2	0	0
	Focal necrosis	2	3	0	0	0	1	2	2	0	3	1	0	0
	Parenchymal congestion	1	0	1	2	0	1	0	3	0	0	0	0	0
	Pigment deposition	1	0	0	2	0	0	0	0	0	0	0	0	0
	ODI		21	22	23	26	17	14	24	14	12	17	4	0
Kidney	Vacuolar degeneration	1	1	0	1	2	1	1	0	1	1	2	0	0
	Hydropic degeneration	1	3	2	1	0	1	3	0	3	0	2	0	0
	Pigment deposition	1	3	1	1	1	0	2	0	1	1	0	0	0
	Parenchymal necrosis	3	0	0	0	3	0	0	1	0	0	0	0	0
	ODI		7	3	3	12	2	6	3	5	2	4	0	0

Pi: Pathological index of each lesion according to their importance to organ function [38].

N _OL: number of fishes displaying one type of organ lesion (OL).

^∗ODI: sum of lesions observed for each organ taking into account their relative severity and the number of fishes (N_OL).