Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structure of FIX. S – signal peptide; P – propeptide, Gla – Gla domain, EGF1 and EGF2 – epidermal growth factor-like domains, AP – activation peptide, Protease – serine protease domain. Posttranslational modifications sites: Gla – γ-carboxylation, Hya – β-hydroxylation; S – sulfation, P – phosphorylation, ♦ – N-linked and ● – O-linked glycosylation, cleavage points are indicated by triangles, main possible routes for factor IX production or activity improvement are typed in grey.
