Figure 2. Aneurysm induction by CaPO4 treatment in mouse model.
Mice were subjected to AAA induction with CaCl2 or CaPO4 and were sacrificed at indicated time points as described in Materials and Methods. A) Representative pictures of arterial dilation 7 days after surgery. B) Quantification of arterial expansion measured 3, 7, 28, and 42 days after surgery. Fold Change = Maximum Diameter/Pre-surgery diameter. *p < 0.05, n =6. C) Van Gieson’s stain depicting elastin layer degradation in representative treated arteries 7 days after surgery. Scale bar 1003m. D) Semi-quantification of elastin degradation in arteries harvested 7 days after surgery.