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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Exp Mol Pathol. 2012 May 15;93(2):220–226. doi: 10.1016/j.yexmp.2012.03.014

Figure 6. Anti-CD36 antibody inhibits sub-endothelial foam cell development.

Figure 6

Monocytes prepared within 2×105 PBMC from six independent donors were added to confluent monolayers of HUVEC on collagen gels and allowed to undergo TEM across unstimulated HUVEC for 1 hour as above. The monocyte/HUVEC co-cultures were then incubated with 10 ng/ml TNF-α and either 10 ng/ml anti-CD36 clone FA6-152 or isotype-matched control mouse IgG1, and cultured for a further 48h prior to enumeration of sub-endothelial foam cells. Statistical analysis is a paired Student’s t test.