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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Contemp Clin Trials. 2012 May 9;33(5):860–868. doi: 10.1016/j.cct.2012.05.001

TABLE 1.

Frequency of procedures and details of their inconvenience units on payments made to research participants in the intramural program of the NIH Clinical Center from August 2004 to August 2008. Data collected by the NIH CRVP.

PROCEDURE1 OBSERVATIONS
N (%)
INCONVENIENCE UNITS
Mean (± SD)
Median (25th percentile, 75th percentile)
Range (minimum-maximum)
Aphaeresis 90 (0.25) 8.06 ± 4.52
8.00 (4.00, 11.00)
2–20
Biopsy2 65 (0.18) 5.63 ± 1.61
5.00 (5.00, 8.00)
3–8
Blood draw 5,212 (14.37) 2.25 ± 1.80
2.00 (1.00, 2.00)
0–21
Dual energy x-ray absorptiometry scan (DEXA) 291 (0.80) 3.30 ± 2.19
2.00 (2.00, 6.00)
1–9
Electrocardiography (EKG) 1,156 (3.19) 2.16 ± 2.01
1.00 (1.00, 4.00)
0–10
Electroencephalogram (EEG) 452 (1.25) 5.35 ± 16.70
3.00 (2.00, 4.00)
0–128
Electromyography (EMG) 242 (0.67) 3.37 ± 5.63
1.00 (1.00, 4.00)
0–39
Functional magnetic resonance imaging scan (fMRI) 204 (0.56) 7.07 ± 3.47
10.00 (5.00, 10.00)
0–10
History and physical 3,098 (8.54) 2.02 ± 2.10
1.00 (1.00, 2.00)
0–30
Intravenous line (IV) 1,976 (5.45) 4.44 ± 2.59
4.00 (3.00, 5.00)
0–39
Lumbar puncture (LP) 48 (0.13) 16.92 ± 19.49
5.00 (1.00, 29.00)
1–57
Magnetic resonance imaging scan (MRI) 9,434 (26.01) 5.32 ± 3.69
5.00 (4.00, 5.00)
0–40
Magnetoencephalogram (MEG) 257 (0.71) 3.72 ± 1.86
3.00 (3.00, 4.00)
0–8
Positron emission tomography scan (PET) 1,641 (4.52) 10.41 ± 6.83
10.00 (5.00, 13.00)
1–65
Psychological/cognitive testing 3,883 (10.70) 2.99 ± 2.11
3.00 (2.00, 3.00)
0–21
Serial blood draw 194 (0.53) 4.85 ± 4.56
3.00 (2.00, 7.00)
1–40
Structured clinical interview for DSM (SCID) 385 (1.06) 1.47 ± 0.59
1.00 (1.00, 2.00)
0–5
24 Hour urine collection 224 (0.62) 1.99 ± 1.35
2.00 (1.00, 2.00)
0–10
Ultrasound 116 (0.32) 1.36 ± 0.75
1.00 (1.00, 2.00)
0–5
Urinalysis 873 (2.41) 1.42 ± 0.92
1.00 (1.00, 2.00)
1–14
Videofluoroscopy 35 (0.10) 7.17 ± 5.81
4.00 (4.00, 12.00)
2–21
1

Procedures were selected based on the following criteria: easily identifiable, used standard nomenclature, frequently used in clinical research studies, and had inconvenience units assigned for payment purposes. Medline Plus used for names of abbreviated procedures.

2

Does not include biopsies of major organs such as liver, kidney, etc.