Table 2.
Types of virus particles produced during wild-type HCMV infection.
Nuclear | Cytoplasmic | ||||
---|---|---|---|---|---|
A-capsids | B-capsids | C-capsids | Dense bodies | NIEP | Virion |
Lack scaffold as well as viral DNA and are believed to result from abortive viral DNA encapsidation | Contain scaffold but lack viral DNA; likely to result from abortive capsid formation or DNA encapsidation | Contain viral DNA and lack scaffold; likely representing nucleocapsids in the process of maturation | Noninfectious capsidless particles and carry pp65 tegument protein as the main constituent | Noninfectious enveloped particles (NIEP) produced when B-capsids mature | Infectious virus particles produced when C-capsids mature, containing encapsidated viral DNA. |
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