Table 3.
MAIN EFFECT OF GROUP: SIGNIFICANT CLUSTERS: p=.01 corrected for multiple comparisons
| Brain Region | BA | k | Peak Z | x,y,z | Direction |
|---|---|---|---|---|---|
|
| |||||
| R superior frontal (DLPFC) | 10 | 887 | 3.97 | 18, 65,17 | HC>BD |
| R middle frontal gyrus | 46 | 3.59 | 44,38,15 | ||
| R medial prefrontal | 10 | 4.32 | 12,66,4 | ||
| R middle occipital gyrus | 19/18 | 1595 | 3.86 | 46,−81,11 | HC>BD |
| R fusiform gyrus | 19 | 3.66 | 42, −72, −12 | ||
| R inferior occipital gyrus | 18 | 3.53 | 36, − 93,0 | ||
| L middle occipital gyrus | 19 | 789 | 5.68 | −40, −85,8 | HC>BD |
| L fusiform gyrus
|
19
|
|
4.59
|
−44, −83,6
|
|
| R amygdala | 441 | 4.68 | 30, −1, −18 | BD>HC | |
| R parahippocampal gyrus | 34 | 4.36 | 30,3, −17 | ||
| R superior temporal gyrus | 38 | 4.09 | 32,3, −17 | ||
| R uncus | 28 | 3.87 | 32,5, −19 | ||
| R globus pallidum | 3.60 | 20, −6, −3 | |||
| L superior parietal lobe | 7 | 536 | 4.96 | −28, −65,57 | BD>HC |
| L inferior parietal lobe | 40 | 4.27 | −65, −41,26 | ||
| L supramarginal gyrus | 40 | 3.76 | −63, −43,28 | ||
| L precentral gyrus | 4 | 3.53 | −51, −7,52 | ||
| L middle frontal gyrus | 6/8 | 3.40 | −50,8,46 | ||
| L Caudate Tail | 536 | 4.05 | −20, −32,15 | BD>HC | |
| L Thalamus (pulvinar nucleus) | 3.89 | −18, −32,13 | |||
| R superior parietal lobe | 7 | 2006 | 4.14 | 22, −61,62 | BD>HC |
| R inferior parietal lobe | 40 | 4.13 | 48, −33,35 | ||
| R postcentral gyrus | 5 | 4.04 | 36, −42,59 | ||
| R supramarginal gyrus | 40 | 3.82 | 65, −45,26 | ||
| R precentral gyrus | 44/6 | 1761 | 4.34 | 48,2,7 | BD>HC |
| R insula | 13 | 4.04 | 44,2,5 | ||
| R anterior cingulate cortex | 32 | 439 | 3.77 | 10,45,0 | BD>HC |
| R superior medial frontal gyrus | 10 | 3.67 | 14,45,3 | ||
| R orbital frontal | 11 | 3.67 | 24,37, −5 | ||
| L orbital frontal cortex | 11 | 3.48 | −20,42, −8 | ||
| L cerebellum | 652 | 3.55 | −22, −44, −21 | BD>HC | |
| L/R Brainstem and midbrain | 0, −27, −26 | ||||
Note: Significant clusters: p = .01 corrected for multiple comparisons. BA=Brodmann’s Area; BD=bipolar disorder; DLPFC=dorsolateral prefrontal cortex; HC=healthy control; L=left; R=right; STS=superior temporal sulcus.