Table 5.
Demographic, anthropometric, serum and urinary characteristics of calcium stone-forming subjects from Dallas with and without the MSa
| No MS (N = 82) | MS (N = 46) | P | |
|---|---|---|---|
| Gender, male/female; n ( % ) | 44/38 (52/48) | 28/18 (60/40) | 0.4 |
| Ethnicity, White/Asian/Hispanic/American Indian | 75/1/4/2 | 43/1/2/0 | 0.7 |
| Age, years | 42 ± 12 | 45 ± 11 | 0.2 |
| BMI, kg/m2 | 25.9 ± 5.1 | 35.4 ± 9.6 | < 0.0001 |
| Systolic BP, mmHg | 121 ± 14 | 128 ± 13 | 0.01 |
| Diastolic BP, mmHg | 75 ± 9 | 82 ± 9 | 0.001 |
| Serum | |||
| Glucose, mmol/L | 5.0 ± 0.4 | 5.8 ± 1.5 | 0.0004 |
| Triglycerides, mmol/L | 1.14 ± 0.58 | 2.70 ± 1.58 | < 0.0001 |
| HDL cholesterol, mmol/L | 1.35 ± 0.45 | 1.07 ± 0.20 | < 0.0001 |
| Urine | |||
| Total volume, L/day | 1.87 ± 1.00 | 2.19 ± 1.33 | 0.2 |
| Calcium, mmol/day | 5.8 ± 2.9 | 6.1 ± 3.5 | 0.50 |
| Oxalate, mmol/day | 353 ± 141 | 454 ± 206 | 0.004 |
| Uric acid, mmol/day | 3.28 ± 1.12 | 3.79 ± 1.52 | 0.05 |
| pH | 6.14 ± 0.42 | 5.91 ± 0.44 | 0.005 |
| Citrate, mEq/day | 7.5 ± 4.6 | 8.0 ± 5.7 | 0.6 |
| Sulfate, mmol/day | 17.9 ± 7.6 | 20.1 ± 10.2 | 0.2 |
| NAE, mEq/day (calculated) | 43.7 ± 22.0 | 58.0 ± 32.0 | 0.009 |
| NH4+/NAE | 0.79 (0.68–0.92) | 0.68 (0.60–0.82) | 0.02 |
| Creatinine clearance, mL/s | 1.77 ± 0.47 | 2.05 ± 0.73 | 0.02 |
| Supersaturation indices | |||
| SI CaOx (volume adjusted) | 4.45 ± 1.94 | 5.47 ± 3.00 | 0.04 |
| SI Br (volume adjusted) | 1.53 ± 0.87 | 1.45 ± 0.91 | 0.6 |
aValues are expressed as mean ± SD.