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. 2012 Apr 1;3(2):73–79. doi: 10.4161/sgtp.19301

graphic file with name sgtp-3-73-g4.jpg

Figure 4. Parallel regulation of multiple GTPases by syndecan-4. Engagement of syndecan-4 triggers early signals (bold): RhoG, Rac1 and RhoA inhibition, followed by late signals: Arf6 and RhoA activation.