Table 1.
Geometric mean PSA and age-adjusted ratio of geometric mean (RGM) PSA in a population-based cohort of men from King County, WA
| N | Geometric Mean | RGM (95% CI) | |
|---|---|---|---|
| Age | |||
| 40 – 49 | 75 | 0.68 | 1.00 (referent) |
| 50 – 54 | 93 | 0.83 | 1.23 (0.94 – 1.61) |
| 55 – 59 | 149 | 0.94 | 1.39 (1.08 – 1.78) |
| 60 – 64 | 152 | 1.13 | 1.66 (1.30 – 2.13) |
| 65 – 69 | 163 | 1.14 | 1.68 (1.32 – 2.14) |
| 70 – 74 | 138 | 1.83 | 2.70 (2.10 – 3.46) |
| BMI category | |||
| Normal (< 25) | 219 | 1.18 | 1.00 (referent) |
| Overweight (25 – 29) | 363 | 1.13 | 0.96 (0.83 – 1.11) |
| Obese (≥ 30) | 188 | 0.94 | 0.83 (0.70 – 0.99) |
| Race | |||
| Caucasian | 704 | 1.10 | 1.00 (referent) |
| African-American | 66 | 0.99 | 1.17 (0.93 – 1.49) |
| Family history of prostate cancer+ | |||
| No | 679 | 1.06 | 1.00 (referent) |
| Yes | 91 | 1.34 | 1.27 (1.04 – 1.54) |
| Diabetes mellitus | |||
| No | 693 | 1.10 | 1.00 (referent) |
| Yes | 77 | 1.00 | 0.85 (0.69 – 1.05) |
| BPH * | |||
| No | 599 | 0.97 | 1.00 (referent) |
| Yes | 171 | 1.63 | 1.45 (1.25 – 1.70) |
| Statin use (current) | |||
| No | 578 | 1.10 | 1.00 (referent) |
| Yes | 192 | 1.06 | 0.83 (0.72 – 0.97) |
| Aspirin use (current) | |||
| No | 415 | 1.06 | 1.00 (referent) |
| Yes | 355 | 1.13 | 0.88 (0.77 – 1.00) |
| other NSAID use (current) | |||
| No | 665 | 1.03 | 1.00 (referent) |
| Yes | 105 | 0.96 | 0.85 (0.71 – 1.02) |
| Aspirin or other NSAID use (current) | |||
| No | 364 | 1.08 | 1.00 (referent) |
| Yes | 406 | 1.10 | 0.84 (0.73 – 0.95) |
| Thiazide use | |||
| No | 704 | 1.10 | 1.00 (referent) |
| Yes | 66 | 1.00 | 0.85 (0.68 – 1.06) |
+
First-degree relative with prostate cancer
*
Self-reported history of a physician’s diagnosis of benign prostatic hyperplasia