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. 2012 Aug;140(2):109–137. doi: 10.1085/jgp.201210802

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© 2012 DiFranco et al.

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Figure 1. — Delayed rectifier K currents in FDB fibers. (A) IK_V recorded in response to depolarizations from V_H to membrane potential values ranging from −30 to 110 mV in 20-mV steps (gray to orange traces). The NMG-Tyrode contained no Ca²⁺ channel blockers. Linear leak and capacitances were removed from each raw current record by subtracting a scaled version of the current record obtained in response to a 50-mV pulse. (B) Voltage dependence of the peak IK_V (closed circles) and peak gK_V (open circles). For both plots, the circles are connected with straight lines. (C) Voltage dependence of the mean peak IK_V obtained from 16 voltage families in 14 different fibers. (D) Voltage dependence of the mean peak gK_V (circles), calculated from the data in C. The green trace is a single Boltzmann fit to the data with the following parameters (mean ± SD): A = 4.77 ± 0.9 mS/cm²; V1 = 18.2 ± 6.3 mV; K1 = 20.4 ± 1.5 mV. The black trace is a double Boltzmann fit to the data with the following parameters: A = 4.93 ± 0.9 mS/cm²; ε = 0.36 ± 0.06; V1 = −7 ± 4.7 mV; K1 = 6.7 ± 1.1 mV; V2 = 39 ± 6.6 mV; K2 = 19.9 ± 2.3 mV. The red and blue traces are the independent components of the double Boltzmann function. Error bars represent SEM.