Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Aug;140(2):109–137. doi: 10.1085/jgp.201210802

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 DiFranco et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 8. — Radial cable predictions of IK_V and TTS membrane potential changes in intact fibers using multistate models of K channels. (A) di-8-ANEPPS transients recorded in the presence of NMG-Tyrode. The fiber was depolarized in 20-mV steps from −90 (V_H) to 110 mV. (B) Model predictions of the mean TTS voltage (see Appendix) for the same conditions as in A, and assuming the same value of gK_V for the sarcolemma and TTS membranes (0.97 mS/cm²). The model parameters for channels A and B are those in Table A1 of the Appendix. (C) Model predictions of the mean TTS voltage, assuming that gK_V (3.88 mS/cm²) is located exclusively at the surface membrane. (D) IK_V recorded simultaneously with the optical data in A. (E and F) The predicted currents corresponding to the optical simulations in B and C are shown in E and F, respectively. The same color code is used for electrical and optical data.