Table 2. Agreement between different techniques for the diagnosis of S. mansoni infections.
Setting A | Setting B | Setting C | All settings A-B-C | ||||||||||||||
Diagnostic test | Test result | Nine Kato-Katz thick smears | Nine Kato-Katz thick smears | Nine Kato-Katz thick smears | Nine Kato-Katz thick smears | ||||||||||||
Positive | Negative | K* | P-value | Positive | Negative | K* | P-value | Positive | Negative | K* | P-value | Positive | Negative | K* | P-value | ||
One Kato-Katz (stool day 1) | Positive | 29 | 0 | 0.63 | 8.8 10−16 | 100 | 0 | 0.42 | 4.4 10−16 | 76 | 0 | 0.4 | 3.1 10−15 | 205 | 0 | 0.47 | 0 |
Negative | 21 | 88 | 76 | 69 | 79 | 87 | 176 | 244 | |||||||||
Three Kato-Katz (stool 1) | Positive | 33 | 0 | 0.71 | 0 | 120 | 0 | 0.54 | 0 | 108 | 0 | 0.62 | 0 | 261 | 0 | 0.62 | 0 |
Negative | 17 | 88 | 56 | 69 | 47 | 87 | 120 | 244 | |||||||||
One CCA (urine day 1) | Positive | 41 | 31 | 0.42 | 1.14 10−7 | 145 | 26 | 0.43 | 7.1 10−12 | 136 | 37 | 0.47 | 7.6 10−14 | 322 | 94 | 0.47 | 0 |
Negative | 9 | 57 | 31 | 43 | 19 | 50 | 59 | 150 | |||||||||
Three CCA | Positive | 46 | 40 | 0.4 | 5.84 10−8 | 160 | 45 | 0.29 | 9.8 10−7 | 149 | 60 | 0.31 | 3.4 10−9 | 355 | 145 | 0.37 | 0 |
Negative | 4 | 48 | 16 | 24 | 6 | 27 | 26 | 99 | |||||||||
One CCA-L | Positive | 23 | 0 | 0.52 | 3.1 10−12 | 121 | 6 | 0.49 | 0 | 86 | 7 | 0.41 | 3.3 10−13 | 230 | 13 | 0.5 | 0 |
Negative | 27 | 88 | 55 | 63 | 69 | 80 | 151 | 231 |
k<0 indicating no agreement, k = 0–0.2 indicating poor agreement, k = 0.21–0.4 indicating fair agreement, k = 0.41–0.6 indicating moderate agreement, k = 0.61–0.8 indicating substantial agreement, and k = 0.81–1 indicating almost perfect agreement.