Figure 5. Validation of predictions of passive surveillance: molecular typing data from ORHs and from the 003/004 studies.
Flowchart (A) illustrates laboratory and typing data available for consecutive faecal samples with positive C. difficile toxin tests in the Oxford site during the 2007 calendar year. Diagnosis peripheral blood neutrophil counts in ST1/NAP1/027 versus non-ST1/NAP1/027 cases are shown for three cohorts: Oxford in 2007, US patients entered into the 003/004 fidaxomicin studies, and Canadian patients entered into the same trials. (B) Means and standard errors in each group are shown, as are (C) 95% CIs around the difference between ST1/NAP1/027 versus non-ST1/NAP1/027 cases.