Table 1. Regional activations and deactivations for cigarette-cue contrasts.

	High craving smokers					Moderate craving smokers
	Peak x	Peak y	Peak z	Peak t-value	Voxels	Peak x	Peak y	Peak z	Peak t-value	Voxels
Partner-cig vs. Partner-pen
Activations
left posterior cingulate						−6	−57	16	9.14	118
left middle temporal gyrus						−40	−64	13	5.29	69
Deactivations
right precuneus	14	−70	41	−7.04	461
left inferior parietal gyrus	−46	−43	41	−7.70	342
left inferior frontal gyrus	−46	2	31	−10.56	171
left insula	−43	−37	20	−6.89	90
Acquaintance-cig vs. Acquaintance-pen
Activations
bilateral posterior cingulate						−1	−61	17	11.19	556
left supramarginal gyrus						−49	−55	32	8.36	140
right medial frontal gyrus						8	44	14	6.64	81
left superior frontal gyrus						−16	47	26	6.28	71
left anterior cingulate						−10	44	9	4.63	67
Deactivations
left superior parietal lobule	−31	−73	50	−5.09	154
right superior parietal lobule	41	−58	50	−4.45	112

Whole brain analyses results for cigarette-cue contrasts. Coordinates are Talairach. We accepted p<0.05 (FWE-corrected) for the single peak voxel in a cluster with a minimum of 65 voxels (high craving group) and 67 voxels (moderate craving group). We also highlight several smaller clusters of interest that did not meet the minimum voxel size set by our Monte Carlo simulations. These smaller clusters were identified using a threshold of p<0.01 uncorrected, and we use an * in this table to indicate these smaller clusters of interest.