Table 2. SIRT gene expression in human biopsies.

	Human AK	SCC
	Fold difference relative to normal adjacent tissue
	(Mean ± SEM)
SIRT1	1.4±0.1	4.8±1.5*
SIRT2	3.5±1.6*	4.3±2.2*
SIRT3	5.7±2.8*	3.4±0.7*
SIRT4	2.9±2.3	4.5±1.0*
SIRT5	2.1±0.4*	8.4±2.6*
SIRT6	17.8±8.3*	8.7±2.8*
SIRT7	7.9±3.8*	15.7±7.4*

qPCR analyses of SIRT genes in skin biopsies.

Difference from normal adjacent tissue at *p<0.05 and a fold change of >1.5 or <0.67. n = 3 human biopsies each for AK and n = 5 for SCC, analyzed in triplicate.