Figure 3. Estimate of the ADH1 paralog duplications relative to the time of the major primate speciation events.

The average pairwise distances separating the introns of the ADH1 paralogs were compared with the average pairwise distances separating a set of introns in paired taxa. (A) This schematic illustrates the various ortholog comparisons used to estimate the relative age among the ADH1 paralogs. (B) This plot summaries the data in Table 2 and 3. The distances among the ADH1 paralogs in marmoset, macaque and human (black diamonds) are somewhat larger than those separating catarrhine and platyrrhine orthologs (green circles), implying that these ADH1 paralogs diverged (duplicated) before the catarrhine-platyrrhine split. Conversely, distances separating the ADH1 paralogs in marmoset, macaque and human are somewhat smaller than those separating orthologous introns among strepsirhine and haplorhine (red squares), implying that these ADH1 paralogs diverged after the split between strepsirhine and haplorhine.