Table 1. Pairwise distance estimates of ADH1 intronic regions.

paralog	1: HumanADH1A	2: HumanADH1B	3: HumanADH1C	4: MacADH1.0	5: MacADH1.1	6: MacADH1.2	7: MacADH1.3	8: MacADH1.4	9: CalADH1.1	10: CalADH1.2	11: CalADH1.3	12: CalADH1.4
1: Human ADH1A		[0.003]	[0.004]	[0.005]	[0.002]	[0.004]	[0.003]	[0.004]	[0.004]	[0.004]	[0.004]	[0.004]
2: Human ADH1B	0.123		[0.004]	[0.005]	[0.004]	[0.003]	[0.003]	[0.005]	[0.004]	[0.004]	[0.004]	[0.003]
3: Human ADH1C	0.143	0.139		[0.004]	[0.004]	[0.004]	[0.004]	[0.003]	[0.004]	[0.004]	[0.004]	[0.004]
4: Mac ADH1.0	0.134	0.146	0.155		[0.005]	[0.005]	[0.006]	[0.005]	[0.004]	[0.004]	[0.006]	[0.005]
5: Mac ADH1.1	0.059	0.134	0.153	0.143		[0.003]	[0.003]	[0.004]	[0.004]	[0.004]	[0.005]	[0.004]
6: Mac ADH1.2
7: Mac ADH1.3	0.139	0.072	0.153	0.163	0.151			[0.004]	[0.004]	[0.004]	[0.004]	[0.004]
8: Mac ADH1.4	0.152	0.146	0.065	0.164	0.16	0.158	0.158		[0.005]	[0.005]	[0.005]	[0.004]
9: Cal ADH1.1	0.149	0.169	0.171	0.129	0.158	0.178	0.187	0.179		[0.004]	[0.005]	[0.004]
10: Cal ADH1.2	0.127	0.154	0.170	0.164	0.132		0.170	0.179	0.158		[0.004]	[0.005]
11: Cal ADH1.3	0.146	0.124	0.169	0.175	0.157		0.141	0.176	0.183	0.152		[0.004]
12: Cal ADH1.4	0.165	0.161	0.12	0.184	0.173	0.175	0.177	0.127	0.185	0.183	0.172

Pairwise distance among the ADH1 paralogs for the concatenated intronic dataset were calculated using the Maximum Composite Likelihood method implemented by MEGAv4.0. Pairwise distances are shown in the lower left of the table, with variance estimates in the upper right of table.