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. 2012 Aug;22(8):1541–1548. doi: 10.1101/gr.135541.111

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© 2012, Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported License), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 6. — Application to ENU-induced mouse mutant. (A) Homozygosity scoring reveals a single peak on chromosome 2. (B) Log likelihood analysis highlights a 5.5-Mb interval harboring a single nonsynonymous change in the candidate gene Lrp2.