Table 1.

Anti-FXa activity in plasma of patients carrying P1 mutations and controls after 3 d of incubations at 37°C and 42°C.^a

	Anti-FXa activity, %b
	37°C	42°C	Activity reduction, %c
Control	100.0 ± 5.1	73.5 ± 3.7	26.5
Δ393	47.8 ± 2.3	28.4 ± 2.2	40.6
R393H	54.8 ± 1.8	21.3 ± 3.5	61.1
R393C	50.5 ± 1.1	25.3 ± 4.1	49.9

^aData are mean ± SD of three independent measurements.

^bPercentage of the activity observed in a pool of 100 healthy subjects.

^cReduction of activity induced by heating at 42°C and considering the value observed at 37°C for control plasma as 100%.