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. Author manuscript; available in PMC: 2013 Aug 1.

Published in final edited form as: Am J Transplant. 2012 May 11;12(8):2017–2028. doi: 10.1111/j.1600-6143.2012.04073.x

Groups of wild-type C57BL/6 (— n = 8) and B6.CCR5^−/− (--- n = 7) mice received cardiac allografts from B6.K^d donors. (A) Graft survival was monitored daily by abdominal palpation and rejection confirmed by laparotomy. (B) On day 10 post-transplant, B6.K^d allografts were harvested from randomly selected wild-type and B6.CCR5^−/− recipients. Methanol-fixed sections were prepared and stained with hematoxylin and eosin. Prepared frozen sections were stained to detect the presence of CD4 and CD8 T cells and Ly-6G⁺ cells that are primarily neutrophils. Sections shown are representative of 3–4 grafts from each group. Magnification, 200×.

Groups of wild-type C57BL/6 (— n = 8) and B6.CCR5^−/− (--- n = 7) mice received cardiac allografts from B6.K^d donors. (A) Graft survival was monitored daily by abdominal palpation and rejection confirmed by laparotomy. (B) On day 10 post-transplant, B6.K^d allografts were harvested from randomly selected wild-type and B6.CCR5^−/− recipients. Methanol-fixed sections were prepared and stained with hematoxylin and eosin. Prepared frozen sections were stained to detect the presence of CD4 and CD8 T cells and Ly-6G⁺ cells that are primarily neutrophils. Sections shown are representative of 3–4 grafts from each group. Magnification, 200×.