Appendix 1.
Search terms with regard to exposure, outcome and study design
| Exposure | Outcome | Study design | ||
|---|---|---|---|---|
| “Fructose”[Mesh] OR | Glucose tolerance and insulin sensitivity | “Randomized Controlled Trial”[Publication Type] OR | ||
| “Sucrose”[Mesh] OR | “Hyperglycemia”[Mesh] OR | randomized[Title/Abstract] OR | ||
| “Dietary Sucrose”[Mesh] OR | “Glucose Intolerance”[Mesh] OR | “randomized clinical trial”[Title/Abstract] OR | ||
| “sugar sweetened drinks”[Title/Abstract] OR | “Blood Glucose”[Mesh] OR | “Cohort Studies”[Mesh] OR | ||
| soft drink*[Title/Abstract] OR | “impaired fasting glucose”[Title/Abstract] OR | “Prospective Studies”[Mesh] OR | ||
| refined sugar*[Title/Abstract] OR | “high fasting glucose”[Title/Abstract] OR | “Epidemiologic Studies”[Mesh] OR | ||
| Sugar*[Title/Abstract] | “fasting plasma glucose”[Title/Abstract] OR | controlled[Title/Abstract] OR | ||
| “Hemoglobin A”[Mesh] OR | cohort[Title/Abstract] OR | |||
| “Hemoglobin A, Glycosylated”[Mesh] OR | prospective[Title/Abstract] OR | |||
| “glycosylated”[Title/Abstract] OR | observational[Title/Abstract] OR | |||
| “Insulin Resistance”[Mesh] OR | risk[Title/Abstract] OR | |||
| “Hyperinsulinism”[Mesh] OR | incidence[Title/Abstract] OR | |||
| “hyperinsulinemia”[Title/Abstract] OR | incident[Title/Abstract] OR | |||
| “insulin sensitivity”[Title/Abstract] OR | “Risk Factors”[Mesh] | |||
| Insulin [Title/Abstract] OR | ||||
| Serum lipids | ||||
| “Lipoproteins”[Mesh] OR | ||||
| “Lipoproteins, HDL”[Mesh] OR | ||||
| “Lipoproteins, LDL”[Mesh] OR | ||||
| “Triglycerides”[Mesh] OR | ||||
| “Cholesterol”[Mesh] OR | ||||
| “serum lipids”[Title/Abstract] OR | ||||
| Low density lipoprotein* [Title/Abstract] OR | ||||
| High density lipoprotein* [Title/Abstract] OR | ||||
| AND | LDL [Title/Abstract] OR | AND | ||
| HDL [Title/Abstract] OR | ||||
| Inflammation markers | ||||
| “Inflammation Mediators”[Mesh] OR | ||||
| “Inflammation”[Mesh] OR | ||||
| “C-Reactive Protein”[Mesh] OR | ||||
| “Leukocyte Count”[Mesh] OR | ||||
| Blood pressure | ||||
| “Blood pressure”[Mesh] OR | ||||
| “Hypertension”[Mesh] OR | ||||
| Uric acid | ||||
| “Uric acid”[Mesh] OR | ||||
| Uric*[Title/Abstract] OR | ||||
| Type 2 diabetes | ||||
| “diabetes”[Title/Abstract] OR | ||||
| “Diabetes Mellitus”[Mesh] OR | ||||
| “Diabetes Mellitus, Type 2”[Mesh] OR | ||||
| Cardiovascular disease | ||||
| “Cardiovascular Diseases”[Mesh] OR | ||||
| “Myocardial Ischemia”[Mesh] OR | ||||
| “Myocardial Infarction”[Mesh] OR | ||||
| “Stroke”[Mesh] OR | ||||
| “Coronary Disease”[Mesh] OR | ||||
| All-cause mortality | ||||
| “Mortality”[Mesh] OR | ||||
| “Survival”[Mesh] OR | ||||
| “Fatal Outcome”[Mesh] OR | ||||
| “Cause of Death”[Mesh] |