Fig. 3.

The effect of resveratrol (A, D, G), 3,3′,4,4′-THS (B, E, H) and 3,3′,4,4′,5,5′-HHS (C, F, I) on HPMC-dependent migration of endothelial cells (HUVEC, HMVEC, HMEC-1). Endothelial cells were exposed to samples of conditioned medium from young and senescent HPMCs, and their migration was examined using Transwell inserts, as described in “Materials and methods”. The asterisks indicate a significant difference compared to the control group. The experiments were performed in triplicates with HPMC cultures derived from 9 to 12 different donors