FIG. 2.
Sample results from the demonstrative case study using the Dexcom SEVEN sensor. Data include 98.5 days with 83 hypoglycemia events (<70 mg/dL [3.9 mmol/L]). (A) True-positive ratio (TPR) values and false-positive rate (FPR) values are shown for three different prediction horizon (PH) values for the numerical logic algorithm (NLA) and the Optimal Estimation (OE) algorithm (15, 30, and 60 min in circles, squares, and triangles, respectively), with NLA with successive alarms required (SAR) of 1 (open symbols), an SAR of 2 (solid symbols), and OE (striped symbols). (B) The relative density of first alarms is shown for the NLA with PH=30 min and SAR=2. (C) The percentage of first alarms that are longer than tW time before the event are shown for NLA and OE with three PH values (15, 30, and 60 min in circles, squares, and triangles, respectively), with an SAR of 1 (solid lines and open symbols), an SAR of 2 (dashed lines and filled symbols), and OE (dash-dotted line with striped symbols). The legend entries indicate the algorithm, the SAR, and the PH. Color images available online at www.liebertonline.com/dia