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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Front Biosci. 2010 Jan 1;15:151–165. doi: 10.2741/3612

Fig. 4.

Fig. 4

Two-way directional communication between stroma and epithelium mediated by fibroblast growth factors. Stromal FGF7/FGF10 and epithelial FGFR2IIIb mediate stromal to epithelial signaling, while epithelial FGF9 signaling to stromal FGFR3 completes the two-way conversation. Androgen may differentially modify either the signal or reception in either compartment. Either partitioned FGFR signal may affect reciprocal cross-talk back to the other compartment. FGF, fibroblast growth factor; AR, androgen receptor; HS, cell- and FGFR-specific heparan sulfate (wavy line).