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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Behav Brain Res. 2012 May 9;233(1):191–200. doi: 10.1016/j.bbr.2012.05.001

Figure 5. Exercise increased prepro-galanin mRNA expression in the locus coeruleus.

Figure 5

Exercise rats that were not injected (0x FG7142) exhibit increased (a) optical density for prepro-galanin mRNA in the locus coeruleus compared to sedentary counterparts. Suggesting that long durations of running are needed to increase galanin gene expression, the (b) optical density for prepro-galanin mRNA in the locus coeruleus was positively correlated with distance ran at 3 weeks. (c) The representative photomicrographs show 35S-oligonucleotide binding directed towards prepro-galanin mRNA in the brain of rats that were not injected and either forced to remain in sedentary conditions (left) or allowed access to a running wheel (right) for three weeks. Sections were collected at −10.04 mm from bregma. Scale bar indicates 1 mm. Data are mean ± SEM (n = 9–10). **p < .01 vs. Sedentary 0x FG7142.