Table 1. The melting temperature (Tmobs) of WRN wild type and mutant proteins.

Protein	Tmobs (°C)	ΔTmobs (°C)
WRN wild type	44.5	─
R993A	44.6	+ 0.1
F1037A	44.0	− 0.5
R993A/F1037A	45.4	+ 0.9

These values were obtained from heat denaturation curves of protein. The experiment carried out duplicate and errors are ±1.1 °C. ΔTmobs = Tmobs (mutant) − Tmobs (wild type).