Figure 1. iUBC-KikGR and UBC-KikGR transgene constructs.
A) iUBC-KikGR transgene construct, containing KikGR cDNA driven by the human Ubiquitin C promoter, flanked by 2 concatamerized cHS4 genomic insulator sequences. B) UBC-KikGR transgene construct without genomic insulators. Black box, poly-adenlyation sequence; arrows, transcriptional start site; 2x cHS4, 2 concatamerized cHS4 genomic insulator sequences; KikGR, Kikume green-red cDNA; UBC, human Ubiquitin C regulatory element.