Fig. 1.

Map of the oxe region of B. fragilis. (A) Diagram of the oxe gene (blue box). Predicted protein domains are shown below. Red arrows depict IS4400′ insertions. Shown in the green boxes are the mutations found in spontaneous oxygen-enabled mutants of ADB77, with nucleotide positions in parentheses. Orange boxes denote mutations found in oxygen-enabled mutants from transposon-insertion pool. Purple boxes denote polymorphisms in Oxe sequence from clinical strains. (B) Genomic region surrounding the oxe gene. nagB, glucosamine 6-P deaminase.