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Heat-induced conformational transition in some variant MVM capsid-like particles followed by the variation in tryptophan fluorescence as a function of temperature. (A) Closed circles, WT capsid; squares, mutant L172A; triangles, D58A; inverted triangles, N183A. In the virion, mutation L172A led to a drastically reduced infectivity; mutations D58A and N183A had no severe effect on the infectivity. (B) Closed circles, WT capsid; open circles, cross-linked WT capsid.
