Cumulative probability of overall survival in the total study population (n=1178). (1) Patients in the 1st group with D-dimer levels ranging from minimum to 1st quartile [0.03 to 0.34 μg/mL] of levels in the total study population are compared to (2) those with D-dimer levels in the 2nd group with levels between the 1st and 2nd quartiles [0.34 to 0.71 μg/mL], (3) those in the 3rd group with levels between the 2nd and 3rd quartiles [0.71 to 1.33 μg/mL] and (4) the 4th group with D-dimer levels ranging from the 3rd quartile to maximum [1.33 to 45.1 μg/mL] of D-dimer levels in the study population. Total numbers of patients with D-dimer levels in the 1st, 2nd, 3rd and 4th groups at study inclusion were 304, 327, 253 and 294, respectively.