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Effect of anti-TF antibody on thrombin generation in platelet-free plasma (PFP). Cell lysates were preincubated with 0.09 mg/mL anti-TF antibody or negative antibody and then tested for thrombin generation in PFP. Inhibition of TF determined a more pronounced reduction of thrombin generation in NB4 and MCF-7 cells than in HEL, K562 and H69 cells. Results represent the mean ± SD of three experiments performed in triplicate. *P<0.05 vs. cotrol antibody.
