Table 1.

List of celiac disease-relevant T cell epitopes; the nine amino acid cores are shown, nomenclature according to ref. 45

DQ2.5-restricted epitopes
DQ2.5-glia-α1a	P F P Q P E L P Y
DQ2.5-glia-α1b	P Y P Q P E L P Y
DQ2.5-glia-α2	P Q P E L P Y P Q
DQ2.5-glia-α3	F R P E Q P Y P Q
DQ2.5-glia-γ1	P Q Q S F P E Q Q
DQ2.5-glia-γ2	I Q P E Q P A Q L
DQ2.5-glia-γ3	Q Q P E Q P Y P Q
DQ2.5-glia-γ4a	S Q P E Q E F P Q
DQ2.5-glia-γ4b	P Q P E Q E F P Q
DQ2.5-glia-γ4c	Q Q P E Q P F P Q
DQ2.5-glia-γ4d	P Q P E Q P F C Q
DQ2.5-glia-γ5	Q Q P F P E Q P Q
DQ2.5-glia-ω1	I P F P Q P E Q P F
DQ2.5-glia-ω2	P Q P E Q P F P W
DQ2.5-glut-L1	P F S E Q E Q P V
DQ2.5-glut-L2	F S Q Q Q E S P F
DQ2.5-hor-1	P F P Q P E Q P F
DQ2.5-hor-2	P Q P E Q P F P Q
DQ2.5-hor-3	P I P E Q P Q P Y
DQ2.5-sec-1	P F P Q P E Q P F
DQ2.5-sec-2	P Q P E Q P F P Q
DQ2.5-ave-1	P Y P E Q E E P F
DQ2.5-ave-1b	P Y P E Q E Q P F
DQ8-restricted epitopes
DQ8-glia-α1	E G S F Q P S Q E
DQ8-glia-γ1a	E Q P Q Q P F P Q
DQ8-glia-γ1b	E Q P Q Q P Y P E
DQ8-glut-H1	Q G Y Y P T S P Q

Glutamic acid residues (E) formed by TG2-medited deamidation of Q residues in the native gluten sequences are shown

glia-α α-gliadin, glia-γ γ-gliadin, glia-ω ω-gliadin, glut-L low molecular weight glutenin, glut-H high molecular weight glutenin, hor hordein, sec secalin, ave avenin